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National coverage trends were accelerated because of
2019-05-04
National coverage trends were accelerated because of the contribution of trends in the two poorest quintiles. In middle-income countries, for example, the estimated increase in national trends was around 25% faster as a result of the contribution of poor populations. Increases in coverage in rural a
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While a large number of clinical
2019-05-04
While a large number of clinical trials have been completed or underway, there is a lack of strong evidence of their effectiveness and safety. Some experts pointed out that autologous transplantation may put patients at a risk of receiving the genetically defective immune cells, while allogeneic tra
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br Study limitations Although the
2019-05-04
Study limitations Although the number of CPVT patients enrolled in the present study was small, we documented clearly discernible effects of flecainide on CPVT during exercise testing. The dose of flecainide was adjusted to increase it to the maximum tolerable dose without monitoring serum concen
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br The L type calcium
2019-05-04
The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot
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br Clinical characteristics Brugada syndrome is more common
2019-04-30
Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn
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O efeito mim tico das pr
2019-04-30
O efeito mimético das práticas exercidas pela Igreja Universal teve impacto substancial no campo religioso, influenciando inclusive instituições fora do neopentecostalismo. Por exemplo, mediante este processo, a Igreja católica redobrou esforços para ampliar seu capital político. Neste caso, Emerson
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A critical link exists between
2019-04-30
A critical link exists between awareness of risk, the presence of disease, and steps taken by the patient and clinician to change the natural history of disease. Chronic illnesses such as diabetes mellitus, dyslipidaemia, anaemia and a multitude of endocrinological and rheumatological diseases are
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India s National Programme for Prevention and Control
2019-04-30
India\'s National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Disease and Stroke is an important step to integrate preventative and treatment interventions within the National Health Mission Framework. Reliable, direct monitoring of cause-specific mortality in India is s
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Dyslipidemia is characterized by increased total cholesterol
2019-04-30
Dyslipidemia is characterized by increased total cholesterol, LDL-C, and triglyceride levels, and decreased HDL-C levels. However, the association of ApoA1 polymorphism with serum HDL-C level remains controversial. The polymorphisms of ApoA1+84 TC, but not MspI, are associated with serum HDL-C. The
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CaMKII phosphorylation of L type Ca channels alters
2019-04-30
CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 neuraminidase inhibitor and predisposing to early afterdepolarizations. Recently iden
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br Case report A year
2019-04-30
Case report A 68-year-old man with dilated cardiomyopathy [Left ventricular (LV) ejection fraction, 15%] of unknown etiology and nonsustained ventricular tachycardia was referred to our institution. He was prescribed a β-blocker (2.5mg of carvedilol, which was gradually increased to 20mg) and 200
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Education and lifestyle changes for the prevention of arrhyt
2019-04-30
Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev
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Si se rescata de estas afirmaciones en
2019-04-30
Si se rescata de estas afirmaciones, en primer término, la pretensión crítica realista como fundamento de su propuesta literaria, algunos de los cambios en su entorno cultural cobran relevancia para contextualizar su interés por la ironización de la realidad dentro de la heterogeneidad de su obra. C
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Limitations of meta analyses are often
2019-04-30
Limitations of meta-analyses are often based on the strength of the data available. Only 26% of the eligible studies were judged to be at low risk of overall bias in this analysis. Other studies may have been at low risk for bias but failed to report information necessary for this determination. All
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Sin embargo m s all de las coincidencias sobre qu
2019-04-30
Sin embargo, más allá de las coincidencias sobre qué hacer con y en el exilio, las significativas posiciones que se presentaron en sus páginas estuvieron lejos de mantener una posición unívoca. Como sugirió Gago, en Controversia pueden reconocerse al menos tres figuras: (1) el exilio como privilegio
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