• br Discussion In this study AT originated in

  2019-05-08

  

  Discussion In this study, AT originated in the orifice of the RAA in a patient with ARVC/D. The origins of these ATs were quite close, which is supported by similar P-wave morphology of each AT. The ATs could be ablated by multiple endocardial RF applications. In this case, the exact mechanism un

• br Methods br Results br Discussion br

  2019-05-08

  

  Methods Results Discussion Conclusions Author contributions Disclosures and funding sources Conflicts of interest Introduction Head-up tilt (HUT) testing has become a widely accepted diagnostic tool for the evaluation of neurally mediated syncope (NMS), which is a major cause

• br Case report A year old man with

  2019-05-08

  

  Case report A 67-year-old man with a past history of hepatitis B carrier presented with body weight loss of 10 kg, general weakness and abdominal fullness for three months and was admitted for the impression of decompensated liver cirrhosis. Physical examination of the patient revealed a diffuse

• In a letter to the editor of Dasanu reported the

  2019-05-07

  

  In a letter to the editor of , Dasanu reported the case of a 55-yr-old male diagnosed with t(11;14)+ IgG-lambda MM, who presented with enlarged lymph nodes six years later. Biopsy was consistent with CD5-negative MCL. In 1999, Yamaguchi conducted clonal relationship analysis on myeloma and lymphoma

• br Discussion Valproic acid is a

  2019-05-07

  

  Discussion Valproic ack1 inhibitor is a potent inhibitor of histone deacetylases (HDAC). It can modify the structure of chromatin allowing recruitment of transcription factors to restore epigenetically suppressed genes. Valproic acid has been shown to possess antiproliferative activity and to ove

• adrenergic receptors Currently RFCA is indicated if

  2019-05-07

  

  Currently, RFCA is indicated if pharmacologic therapies are unsuccessful [41]. Myocardial substrates for reentrant VT and/or the origin of focal VT are the ablation target for monomorphic VT storms. Although ablating multiple and unstable VTs is challenging, modern computerized mapping and catheter

• In our clinic the intracardiac

  2019-05-07

  

  In our clinic, the intracardiac electrogram recorded by the ICD showed repetitive non-reentrant ventriculoatrial synchrony (RNRVAS), which was associated with hypotension and chest discomfort (Fig. 1). We suspected that the RNRVAS caused the hypotension; therefore, we performed electrophysiologic an

• br Remote monitoring advantages br

  2019-05-07

  

  Remote monitoring advantages What is obtained by remote monitoring? How should we act? Important factors at the time of informed consent Patients benefit greatly from RM, and they feel secure and safe because they feel connected to the hospital at all times. However, patients may have exces

• In summary we have established an animal model of

  2019-05-07

  

  In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibrom

• Having to seek various approvals with no communication betwe

  2019-05-07

  

  Having to seek various approvals, with no communication between RECs and no plan for which committee\'s decisions take priority, can lead to research bottlenecks. Many RECs, particularly those in low-income and middle-income countries (LMICs), have long turnaround times, perhaps because of infrequen

• Patient a year old man with RAEB

  2019-05-07

  

  Patient 2, a 54-year-old man with RAEB 2, and severe chronic obstructive pulmonary disease, struggled through induction chemotherapy with daunorubicin plus cytarabine (DA) 3+10. Second DA 3+8 produced delayed hematopoietic recovery. CR1 was documented after course 1 and lasted 18 months. Relapse was

• br Authorship br Conflict of interest

  2019-05-07

  

  Authorship Conflict of interest Acknowledgments The Leukemia & Lymphoma Society supported CRC with a Scholar in Clinical Research award (2400-13). This work was supported by the Gatorade Trust from the University of Florida Department of Medicine. Introduction Klinefelter syndrome (KS),

• thymidylate synthase inhibitor The re treatment of metastati

  2019-05-07

  

  The re-treatment of metastatic bone disease causing recurrent pain after an initial course of EBRT was seen to be feasible with a reasonable rate of symptom relief [13–19]. In echoing the ACR findings, the task force noted that the available data was derived from studies where re-treatment was not t

• Preference for injectable therapy over oral therapy

  2019-05-07

  

  Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne

• Introduction Metastasis to the bone is a common complication

  2019-05-07

  

  Introduction Metastasis to the bone is a common complication of breast, lung, prostate, gastrointestinal, haematological, melanoma, and other tumours [1–3]. In many patients with primary breast, prostate and lung primary tumours, bone metastases (BoM) are signs associated with the presence of disse

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