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Causative genes for ARVC and their respective characteristic
2019-05-23
Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table
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Additionally the selection for subcutaneous ICD implant is b
2019-05-23
Additionally, the selection for subcutaneous ICD implant is based on pre-implant electrographic body surface mapping. The sensing algorithm for this system depends on the surface elecrtrocardiogram (ECG) morphology, specifically the R-and T-wave amplitudes, R/T and R/P ratios, QRS duration and QT in
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En Latinoam rica donde se presentan intentos
2019-05-23
En Latinoamérica, donde se presentan intentos de fundar identidades regionales o nacionales que ejerzan contrapeso tnf alpha inhibitor los embates de homogeneización cultural, han aparecido diversos criterios relacionados con políticas universalistas o con el cosmopolitismo. Estos criterios sustenta
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br Introduction Multiple signal transduction pathways
2019-05-23
Introduction Multiple signal transduction pathways in normal and malignant BI2536 converge on Bcl-2 family proteins, which stand at the crossroads between cell survival and apoptosis. The seminal event in the intrinsic pathway of apoptosis is mitochondrial outer membrane permeabilization (MOMP),
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mek inhibitor For many decades scientists have warned
2019-05-23
For many decades, scientists have warned that human activity is pushing life on our planet beyond the point of no return. In the Earth\'s history there have been five mass extinction events, most recently the Cretaceous–Tertiary mass extinction that occurred almost 65 million years ago and was thoug
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In the current era nearly all cases of
2019-05-23
In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud
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We also thank Kate Mandeville and
2019-05-22
We also thank Kate Mandeville and Adamson Muula for their letter and agree with the need to ensure resources are available to fund salaries for newly trained doctors and other health workers to allow these workers to be absorbed into the under-resourced Malawian health system. The doctors\' salary c
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Cell adhesion to extracellular matrix
2019-05-22
Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp
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Most forms of AVNRT are created by reentry between
2019-05-22
Most forms of AVNRT are created by reentry between two (or more) atrial connections to the AV node. The fast AV nodal pathway (shortest conduction time) is formed by transitional cells crossing the tendon of Todaro superiorly. Two slow AV nodal pathways are formed by the rightward and leftward infer
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In addition to being a key determinant of the
2019-05-22
In addition to being a key determinant of the risk of acquiring infection, nutritional status is a principal determinant of the health trajectory and outcomes following discharge from hospital. Among Gambian children admitted with pneumonia, even being moderately underweight was associated with a ra
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En este mismo sentido Maryluz Vallejo M afirma que Es
2019-05-22
En este mismo sentido, Maryluz Vallejo M. afirma que: Es decir, el medio de comunicación sí ostentaba una postura política, la diferencia con los otros estaba en que dicha postura lograba congregar annexin v los partidarios de posiciones políticas contrarias y, en lugar de ser objeto de exposición
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En relaci n con lo anterior el
2019-05-22
En relación con lo anterior, el papel de los medios de comunicación en la vigilancia de los asuntos del Estado, Bentham defendía la importancia de hacer públicas las sesiones del Congreso, así como el ataque frontal al secretismo de los gobernantes tradicionales. Es decir, era evidente que para el f
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In a previous report it was speculated that
2019-05-22
In a previous report, it was speculated that withdrawal syndrome after IM cessation was related to a loss of blocking tyrosine kinases, such as c-kit and platelet-derived growth factor receptor (PDGFR) [2]. The inhibition of c-kit and PDGFR by IM reduces and increases the number of osteoclasts and o
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Missed cases have been reported who had an initially elevate
2019-05-22
Missed cases have been reported who had an initially elevated C5DC concentration that normalized on a repeated sample. Such a result may be caused by secondary carnitine depletion. To avoid carnitine depletion, we propose that the carnitine loading test be used to assist diagnosis of GA-1. Although,
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Introduction Despite advances in the treatment of early
2019-05-22
Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant shk [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is multidisciplinary, p
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